Cauterization as a Simple Method for Regeneration Studies in the Zebrafish Heart
نویسندگان
چکیده
منابع مشابه
The zebrafish as a model of heart regeneration.
Regeneration is a complex biological process by which animals can restore the shape, structure and function of body parts lost after injury, or after experimental amputation. Only a few species of vertebrates display the capacity to regenerate body parts during adulthood. In the case of the heart, newts display a remarkable ability to regenerate large portions of myocardium after amputation, al...
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After myocardial infarction in humans, lost cardiomyocytes are replaced by an irreversible fibrotic scar. In contrast, zebrafish hearts efficiently regenerate after injury. Complete regeneration of the zebrafish heart is driven by the strong proliferation response of its cardiomyocytes to injury. Here we show that, after cardiac injury in zebrafish, telomerase becomes hyperactivated, and telome...
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ژورنال
عنوان ژورنال: Journal of Cardiovascular Development and Disease
سال: 2020
ISSN: 2308-3425
DOI: 10.3390/jcdd7040041